Research Highlights
Pharmaceutical Crystallization
Viedma Ripening: The future of deracemization processes
Chirality is a concept well known to chemists and has numerous implications, especially in the pharmaceutical industry. The presence of one enantiomer in a drug can lead to desired or undesired effects in the human body, which is a highly asymmetric environment.
Temperature Cycling - Induced Deracemization
An alternative method for deracemization, is temperature cycling-enhanced-deracemization. According to this technique, a racemic suspension of a conglomerate forming system undergoes symmetry breaking under periodic change of temperature, rather than grinding.
Population Balance Modeling : Mapping Deracemization Processes
As regards modelling, the main goal of my research is to describe the evolution of deracemization processes, using Population Balance Modeling (PBM).
Growth, dissolution and agglomeration of crystals
In this section we focus on decoupling the growth, dissolution and agglomeration processes experimentally. In addition, activity - based Population Balance Models are formulated with a view to extracting the rates of each process and pave the way towards optimization.
